The FDA recently approved the mRNA vaccine Moderna for emergency use authorization to protect against COVID-19. While Phase 1-3 clinical trials showed the vaccine was safe and efficacious, recent stories have been published describing the odd and alarming phenomenon of exaggerated swelling at filler injection sites.
Is the Moderna Vaccine safe after fillers?
While there is no isolated clinical study to evaluate the safety, fillers, in general, are safe and the vaccine independently is safe. The cases of inflammation reported all improved with basic treatments like antihistamine and steroids.
What causes Inflammation after the Moderna vaccine and Filler?
While the FDA data revealed does not specify where or what fillers were used, certain fillers do have more immunogenicity than others. I have studied Vycross® filers such as Volbella® and Vollure® and found that delayed onset nodules are more commonly observed. This reaction is theoretically similar to the inflammation see after Moderna vaccine.

What happens if I get Moderna Vaccine and Fillers?
There were multiple cases of side effects that included inflammation at pain at the site of where fillers had previously been injected, or in one case filler was injected after the vaccination. All of these cases were resolved without serious side effects. It is my belief that they are rare or non-life threatening.
Should I get the Moderna Vaccine if I had fillers?
You absolutely should get the vaccine. While similar case reports have not been reported with the similar Pfizer vaccine, it is my belief that the phenomenon is rare and the vaccines are overall very safe! Disclaimer: The information, including but not limited to, text, graphics, images and other material contained on this website or any affiliated properties are for informational purposes only. The purpose of this information is to promote broad consumer understanding and knowledge of various health topics. It is not intended to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health care provider with any questions. Also, seek advice before undertaking a new health care regimen. Finally, never disregard professional medical advice or delay in seeking it because of something you have read on this website.
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